CU Boulder clinical trial confirms nicotinamide riboside (NR) increases NAD levels and potentially improves heart health.
“Our results also provide initial insight into the effects of chronic NR supplementation on physiological function in humans, and suggest that, in particular, future clinical trials should further assess the potential benefits of NR for reducing blood pressure and arterial stiffness in this group.”— MARTENS, C., ET AL., 2018
Here are just some reasons why researchers are using NR to study the effects of higher NAD levels on human health:
● NAD is used to support healthy DNA and aging through PARP activation
● NAD levels decline by up to 50% in humans between the ages of 40–60
● NAD depletion may play an important role in the aging process 
Like everything else, NAD declines with age. But metabolic stressors that require NAD such as smoking, alcohol consumption, overeating, and sun radiation can speed up that decline.